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EPHB2 — HSPA5

Text-mined interactions from Literome

Ou et al., Eur J Pharmacol 2007 (Carcinoma, Renal Cell...) : Selective inhibitors of ERK , p38 MAPK, and JNK suppressed the induction of GRP78 , CHOP, and PPAR-beta, attenuated indomethacin induced cytotoxicity and reduced increased caspase activity
Jiang et al., Cancer Res 2007 (Melanoma) : Inhibition of MEK/ERK also resulted in down-regulation of GRP78 , which was physically associated with caspase-4, before and after treatment with tunicamycin or thapsigargin
Zhang et al., Cancer Lett 2009 (Adenocarcinoma...) : Thus, activation of MEK/ERK by ER stress is necessary for induction of GRP78 that protects against apoptosis in gastric cancer cells submitted to ER stress