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CCL2 — PRKAA2
Text-mined interactions from Literome
Roca et al., Neoplasia (New York, N.Y.) 2009
(Prostatic Neoplasms) :
The
CCL2 mediated
AMPK regulation decreased raptor phosphorylation ( Ser ( 792 ) ) resulting in hyperactivation of mTORC1 ... By using Akt-specific inhibitor X, it was shown that Akt inactivation did not cause an increase in AMPK phosphorylation in CCL2 stimulated cells, suggesting that
CCL2 mediated negative regulation of
AMPK is independent of Akt
Declèves et al., J Am Soc Nephrol 2011
(Albuminuria...) :
In vitro,
AMPK activation completely
inhibited the induction of
MCP-1 by palmitic acid in mesangial cells