Gene interactions and pathways from curated databases and text-mining

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BDNF — CSF2

Text-mined interactions from Literome

Chiaretti et al., Childs Nerv Syst 2004 (Astrocytoma...) : BDNF instead increases in CSF , while the expression of GDNF remains unchanged both in tissues and in CSF
Bouhy et al., FASEB J 2006 (Paraplegia) : In vitro, BV2 microglial cells expressed higher levels of BDNF in the presence of GM-CSF and neurons cocultured with microglial cells activated by GM-CSF generated more neurites, an effect blocked by a BDNF antibody ... These experiments suggest that GM-CSF could be an interesting treatment option for spinal cord injury and that its beneficial effects might be mediated by BDNF
Mannari et al., Cell Mol Neurobiol 2008 (Body Weight) : In animals treated for 14 days with Duloxetine at 30 and 100 mg/kg, the total BDNF level increased significantly in the prefrontal cortex and CSF , but not in the plasma and serum
Deepa et al., J Neural Transm 2011 (Amyotrophic Lateral Sclerosis) : The present study was aimed to investigate if the ALS-CSF affected the expression of trophic factors namely, brain derived neurotrophic factor (BDNF) , fibroblast growth factor 2 (FGF2) and insulin-like growth factor 1 (IGF1) in the newborn rat spinal cords