Zhou et al., Circ Res 2004
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VEGF activated SREBP1 and SREBP2 in ECs, as demonstrated by the increased SREBPs, their cleavage products, and the upregulation of the targeted genes
Motoyama et al., Biochem Biophys Res Commun 2006
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Moreover, overexpression of SREBP1a dose-dependently suppressed VEGF promoter activity ... These data demonstrated that SREBP1 , activated by atorvastatin, suppressed VEGF expression through the indirect interaction with the proximal tandem Sp1 sites in VSMCs