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RHOA — SLC6A4

Text-mined interactions from Literome

Desbuards et al., Eur J Pharmacol 2009 (Anoxia...) : Western blot, RT-PCR and immunofluorescence analysis revealed a greater expression of 5-HT transporter and ROCK, as well as a greater activation of RhoA in dexfenfluramine-hypoxic rats compared to hypoxic rats
Guilluy et al., Am J Respir Crit Care Med 2009 (Disease Models, Animal...) : Increased Rho kinase activity, RhoA activation, and RhoA serotonylation were also observed in lungs from SM22-5-HTT ( + ) mice, which overexpress 5-HTT in smooth muscle and spontaneously develop PH. Treatment of SM22-5-HTT ( + ) mice with either fasudil or fluoxetine limited PH progression and RhoA/Rho kinase activation