Gene interactions and pathways from curated databases and text-mining

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HLA-DRB1 — PRKDC

Text-mined interactions from Literome

Kim et al., Biochem Pharmacol 2009 : We revealed that siRNA mediated suppression of DNA-PKcs led to decreased phosphorylation of Akt and Bad, a target molecule of Akt, and increased expression of DR4/DR5
Kim et al., Molecular cancer 2011 (Colonic Neoplasms...) : Moreover, the suppression of DNA-PKcs level with siRNA in the cells induced the up-regulation of DR5 and active caspase-8, -9, and -3