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PLD2 — SPHK1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Melendez et al., J Biol Chem 2002
:
Here we also show that
SPHK1 activity
depends on
phospholipase D1 and that FcepsilonRI triggered mast cell degranulation depends primarily on the activation of both phospholipase D1 and SPHK1
Sethu et al., J Immunol 2008
(Calcium Signaling...) :
Using antisense oligonucleotides to reduce specifically the expression of PLD isozymes showed PLD1, but not
PLD2 , to be coupled to TNF-alpha signaling and that PLD1 is
required to mediate receptor activation of
sphingosine kinase and calcium transients