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IL1B — PARP1
Text-mined interactions from Literome
Sharp et al., Inflammation 2001
(Inflammation) :
PARP inhibition with GPI 6150
blocked the
IL-1beta mediated stimulation of both ICAM-1 and E-selectin expression, and blocked TNF-alpha stimulation of ICAM-1 expression at 24 h
GarcĂa et al., Arthritis Res Ther 2006
(Arthritis, Experimental...) :
Interestingly, quantitative real-time PCR and ELISA analysis revealed that the absence of
PARP-1 down-regulated
IL-1beta and monocyte chemotactic protein 1 expression in arthritic joints whereas tumor necrosis factor-alpha transcription was not impaired
Shakibaei et al., Ann N Y Acad Sci 2007
:
Resveratrol inhibits
IL-1 beta induced stimulation of caspase-3 and cleavage of
PARP in human articular chondrocytes in vitro
Huang et al., Biochem Biophys Res Commun 2009
(Disease Models, Animal...) :
Minocycline repressed the expression of TNF-alpha,
IL-1beta , and iNOS, decreased the apoptotic index, and
inhibited poly(ADP-ribose) polymerase-1 ( PARP-1 ) activity in the mouse small intestine