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DUSP1 — NUP43
Text-mined interactions from Literome
Brondello et al., Science 1999
(MAP Kinase Signaling System) :
MKP-1 was a
target in vivo and in vitro for
p42(MAPK) or p44(MAPK), which phosphorylates MKP-1 on two carboxyl-terminal serine residues, Serine 359 and Serine 364
Sakaue et al., J Biol Chem 2004
(MAP Kinase Signaling System) :
Although the phosphorylation or abundance of MEK, an upstream kinase for p42/p44 MAPK, was not altered during differentiation, the abundance of
MAPK phosphatase-1 (MKP-1) , a negative
regulator of
p42/p44 MAPK, was increased with a time course similar to that of the down-regulation of p42/p44 MAPK activity
Bennett et al., Science 1997
:
Overexpression of
MAPK phosphatase-1 (MKP-1) inhibited
p42Erk2 activity and was sufficient to relieve the inhibitory effects of mitogens on muscle-specific gene expression