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ADCYAP1 — LEP
Text-mined interactions from Literome
Yu et al., Peptides 2009
(Inflammation) :
The
effects of
PACAP and related peptides on
leptin , soluble leptin receptor and resistin in normal condition and LPS induced inflammation ... It was also found that, in ordinary condition, treatment with PAC1 agonist maxadilan induced marked increase in serum leptin, leptin : SLR ratios and resistin levels ; while in LPS induced inflammation, VPAC1 mediated much more anti-inflammatory and reversing-LPS
effects of
PACAP on
leptin and resistin than PAC1 and VPAC2 ... It is concluded that different receptors mediates different
effects of
PACAP on
leptin , SLR and resistin in non-inflammatory and LPS induced inflammatory conditions
Tanida et al., Neuroscience 2013
(Body Weight) :
Central
PACAP mediates the sympathetic effects of
leptin in a tissue-specific manner