◀ Back to DAB2
AXIN2 — DAB2
Text-mined interactions from Literome
Hocevar et al., EMBO J 2003
:
Wnt stimulation leads to a time dependent dissociation of endogenous Dab2-Dvl-3 and Dvl-3-axin interactions in NIH-3T3 cells, while
Dab2 overexpression
leads to maintenance of Dab2-Dvl-3 association and subsequent loss of
Dvl-3-axin interactions ... In addition, we find that
Dab2 can associate with axin in vitro and
stabilize axin expression in vivo
Jiang et al., Oncogene 2008
(Carcinoma, Embryonal) :
Ectopic expression of
Dab2 in F9 cells as well as in transformed cell lines
results in increased
Axin expression and attenuation of Wnt mediated signaling