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CXCL10 — VIP

Text-mined interactions from Literome

Juarranz et al., Rheumatology (Oxford) 2004 (Arthritis, Rheumatoid...) : The effects of VIP on basal or tumour necrosis factor alpha (TNF-alpha) stimulated production of CCL2 ( MCP-1, monocyte chemotactic protein 1 ), CXCL8 [ interleukin (IL)-8 ], IL-6 and TNF-alpha were studied by specific ELISAs ( enzyme linked immunosorbent assays )
Delgado et al., FASEB J 2004 : In this study, we investigated the effects of VIP/PACAP on the production of CXCL10 ( a Th1 chemokine ) and of CCL22 ( a Th2 chemokine ) by bone marrow derived dendritic cells ... We found that VIP and PACAP inhibit CXCL10 , while promoting CCL22 production, and that the effects are mediated through the VPAC1 receptor and involve cAMP/PKA as intracellular messengers
Juarranz et al., Arthritis Rheum 2008 (Arthritis, Rheumatoid...) : The expression and function of the potential VIP receptors in FLS were studied by RT-PCR, determination of intracellular cAMP production, cell membrane adenylate cyclase ( AC ) activity, and interleukin-6, CCL2, and CXCL8 production in response to VIP or specific agonists and antagonists