Infantino et al., Biochem Biophys Res Commun 2007
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These results show that SRE/SREBP-1 play a role in the transcriptional regulation of CIC by insulin and PUFA
Damiano et al., Biochem J 2009
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Our data show that PUFA inhibition of hepatic Cic gene transcription is mediated not only by the nuclear level of SREBP-1c , but also might involve a reduction in Sp1 and NF-Y DNA binding, suggesting differential mechanisms in the Cic gene regulation by different PUFA