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GATA2 — NOTCH3

Text-mined interactions from Literome

Kumano et al., Blood 2001 (Leukemia, Erythroblastic, Acute) : These results indicate that GATA-2 activity is necessary for the Notch signaling in hematopoietic cells
Schneider et al., J Pathol 2004 (Burkitt Lymphoma...) : In some leukaemic cell lines, the effect of Notch signalling is mediated by the early transcription factor GATA-2
Guiu et al., J Exp Med 2013 : Together, our findings show that Notch activation in the AGM triggers Gata2 and Hes1 transcription, and next HES-1 protein represses Gata2, creating an incoherent feed-forward loop required to restrict Gata2 expression in the emerging HSCs