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LEP — SLPI

Text-mined interactions from Literome

Nakajima et al., Horm Res 2003 (Obesity) : Prior to semiconfluence, leptin increased [ 3H ] thymidine incorporation while at the semiconfluent and early confluent stages, leptin promoted ALP activity and tended to promote proteoglycan production
Mutabaruka et al., Arthritis Res Ther 2010 (Osteoarthritis) : Exogenous leptin addition stimulated ALP , yet this failed to further increase OC or CICP ... These results suggest that abnormal production of leptin by OA Ob could be responsible , in part, for the elevated levels of ALP , OC, collagen type 1 and TGF-beta1 observed in these cells compared to normal
Zeadin et al., Biochem Biophys Res Commun 2012 : Transfection of BASMCs with an adenovirus that expressed constitutively active GSK-3ß ( Ad-GSK-3ß S9A ) resulted in a > 2-fold increase in GSK-3ß activity and a significant decrease in leptin induced alkaline phosphatase (ALP) activity