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Trayhurn et al., Horm Metab Res 2000
:
Insulin and leptin also stimulated metallothionein production, although the effect was small
Byun et al., Neurobiol Dis 2011
(Body Weight...) :
In the present study, we examined whether metallothionein-3 (Mt3) , a zinc binding protein that is specifically enriched in a brain, plays a role in obesity and hypothalamic leptin signaling in mice ... The present results demonstrate that Mt3 in the brain of male mice, particularly in the hypothalamus, may be involved in central leptin signaling and the consequent increase in peripheral energy expenditure