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IRF6 — PRKCA

Text-mined interactions from Literome

Giroux et al., J Immunol 2000 : Taken together, these results suggest a role for PKC-alpha in the modulation of LPS- and IFN-gamma induced COX-2 expression, as well as in IFN-gamma induced PGE2 secretion
Asehnoune et al., Cell Signal 2005 : Inhibition of PKCalpha/beta also prevented LPS or PGN induced phosphorylation of IKKalpha/beta, phosphorylation and degradation of IkappaB-alpha, as well as phosphorylation of the p65 subunit of NF-kappaB
Chen et al., Int J Biochem Cell Biol 2005 : LPS increased PKC-alpha and -beta activation, and TG pretreatment attenuated LPS stimulated PKC activation
Fronhofer et al., J Leukoc Biol 2006 : In murine macrophages, FcgammaR ligation augmented LPS stimulated activation of PKC-alpha and PKC-delta but reduced IL-12p40 secretion
Zhang et al., Sci China C Life Sci 1997 : Compared with the very recent finding that LPS and PMA trigger the activation and translocation of PKC-alpha and PKC-epsilon, these findings suggest that there is a connection between PKC signaling pathway and the Raf-1/MAPK pathway and that the activation of these main signaling events may be closely related to the secretion of IL-12 during LPS induced modulation of macrophages
Martins et al., Shock 2010 (Diabetes Mellitus, Experimental...) : Relative to control rats, diabetic rats exhibited a significant reduction in the LPS induced phosphorylation of extracellular signal regulated kinase ( 64 % ), p38 ( 70 % ), protein kinase B ( 67 % ), and protein kinase C alpha ( 57 % ) and delta ( 65 % ) and in the expression of iNOS ( 32 % ) and cyclooxygenase 2 ( 67 % ) in the lung homogenates
Lee et al., J Ethnopharmacol 2009 : Then, BV inhibited LPS induced expression of PKC-alpha and MEK/ERK, not p38 and JNK
Lin et al., Shi Yan Sheng Wu Xue Bao 1996 : [ LPS and PMA induced PKC-alpha and PKC-epsilon activation and translocation in murine peritoneal macrophages ]
Chen et al., J Immunol 1998 : Treatment with antisense oligonucleotides for these isoforms further demonstrated the involvement of PKC-alpha , -betaI, and delta, but not -eta, in LPS responses