Gene interactions and pathways from curated databases and text-mining

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F2R — IRF6

Text-mined interactions from Literome

Shinohara et al., Cytokine 2002 : In contrast, IFN gamma or LPS did not affect the PAR-1 mRNA expression
Jesmin et al., Thromb Haemost 2004 (Respiratory Distress Syndrome, Adult) : Of note, LPS induced a rapid and significant increase in levels of PAR-1 compared to control, with a peak level at 1 h ( 3.3-fold )
Pompili et al., Int J Mol Med 2006 : Similarly to astrocytes, both TMT and LPS induced an upregulation of PAR-1 in the rat astrocytoma cell line, C6, thus indicating that this phenomenon was independent from microglial cells eventually contaminating astrocyte primary cultures
Karabiyik et al., Clin Appl Thromb Hemost 2011 : ABS induced sustained PAR-1 down-regulation in the presence of LPS