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CCND2 — IRF6

Text-mined interactions from Literome

Vadiveloo et al., J Interferon Cytokine Res 2000 : We recently showed that LPS unexpectedly induces cyclin D2 in macrophages ... Since LPS stimulates macrophages to produce autocrine acting cytokines, we examined whether LPS induction of cyclin D2 was mediated by one such type of cytokine, type I interferons ( IFN ) ... Consistent with this result, addition of anti-IFN-alpha/beta neutralizing antibodies reduced levels of LPS stimulated cyclin D2 in normal BMM ... Thus, we have identified a new role for type I IFN in macrophages, namely, as essential mediators of LPS stimulated cyclin D2 expression
Smithwick et al., Toxicology 2004 : In addition, PCB mixtures with an increased percentage of chlorines in the ortho position following an environmentally occurring degradation process inhibited LPS induced proliferation, interrupted cell cycle progression, and decreased cyclin D2 expression
Vadiveloo et al., J Biol Chem 1998 : Here we report upon the effect of LPS on expression of cyclin D2 in normal mouse bone marrow derived macrophages ( BMM ) ... Furthermore, LPS alone induced cyclin D2 but not cyclin D1