Gene interactions and pathways from curated databases and text-mining

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ILK — SMAD3

Text-mined interactions from Literome

Li et al., J Clin Invest 2003 (Fibrosis...) : TGF-beta1 induced ILK expression in renal tubular epithelial cells in a time- and dose dependent manner, which was dependent on intracellular Smad signaling
Iwano et al., Curr Opin Nephrol Hypertens 2004 (Fibrosis...) : The intracellular signaling pathways leading to initiation of epithelial-mesenchymal transition remain largely unknown, though recent studies have identified beta-catenin and Smad3 activation of lymphoid enhancer factor, integrin linked kinase , and small GTPases and mitogen activated protein kinases as key components