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CUL5 — DAB1

Text-mined interactions from Literome

Feng et al., Genes Dev 2007 : Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development
Simó et al., J Neurosci 2010 : Here we test whether Cul5 regulates neuron layering by affecting Dab1 stability or other mechanisms ... The effects of Cul5 and Dab1 are cell autonomous, and Cul5 regulates movement of early as well as late cortical neurons ... These results show that Cul5 regulates neuron layering by stimulating Dab1 degradation and that Cul5 controls migration speed and stopping point, and they demonstrate the importance of negative feedback in signaling during cortical development