◀ Back to CRP

CRP — SCD

Text-mined interactions from Literome

Bellocci et al., J Cardiovasc Med (Hagerstown) 2007 (Death, Sudden, Cardiac...) : The CAMI GUIDE study will assess the predictive role of CRP in SCD in patients with previous MI undergoing ICD implantation
Biasucci et al., Eur Heart J 2012 (Death, Sudden, Cardiac...) : The primary objective of the CAMI-GUIDE study is to assess the predictive role of C-reactive protein for SCD or VT/VF in ischaemic patients with the ejection fraction < 30 % and ICDs. Secondary endpoints included all-cause mortality, hospitalizations, and death from heart failure. Additional analyses incorporated cystatin-C and NT-ProBNP in multi-marker approach for the prediction of adverse outcomes. A total of 300 patients were enrolled. All-cause mortality at 2 years was 22.6 %, mortality from heart failure was 8.3 %. Primary endpoint occurred in 17.3 %. At a competing risk multivariable analysis adjusted for baseline variables, no significant difference in primary endpoint was found between patients with C-reactive protein =3 vs. > 3 mg/L [ heart rate ( HR ) 0.91 ( 0.50-1.64 ) P = 0.76 ], while C-reactive protein > 3 mg/L was strongly associated with mortality due to heart failure [ HR : 3.17 ( 1.54-6.54 ) P = 0.002 ]