Gene interactions and pathways from curated databases and text-mining

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COA3 — FASN

Text-mined interactions from Literome

Ide et al., Biofactors 2000 : Dietary fats rich in alpha-18 : 3-CoA relative to safflower oil did not affect the hepatic activity of fatty acid synthase and glucose 6-phosphate dehydrogenase
Agius et al., Biochem Pharmacol 1985 : Since POCA was a more potent inhibitor of fatty acid synthesis than palmitate, but POCA-CoA did not inhibit acetyl-CoA carboxylase more strongly than palmitoyl-CoA, it is suggested that POCA-CoA may inhibit fatty acid synthase directly
Ahmad et al., Biochem J 1982 : Rat mammary-gland fatty acid synthase required free CoA for activity
Clements et al., Biochem J 1982 : Fatty acid synthase from lactating rat mammary gland is rapidly and irreversibly inhibited by S- ( 4-bromo-2,3-dioxobutyl ) -CoA