Gene interactions and pathways from curated databases and text-mining

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CD79A — ITIH4

Text-mined interactions from Literome

Hu et al., Med Microbiol Immunol 1999 : An enhanced IgA response to gp120 in various mucosal organs was recorded after i.n. immunization with gp120 incorporated in RSV ISCOMs, indicating a role of RSV envelope proteins in enhancing and targeting mucosal responses to passenger antigens
Dugas et al., AIDS Res Hum Retroviruses 2000 : It was found that gp120 specifically potentiates in a dose dependent manner IL-4 induced IgE production and does not affect IL-4 induced IgG, IgA , or IgM production
Hu et al., Adv Drug Deliv Rev 2001 : After nasal administration an enhanced mucosal IgA response to gp120 was observed in the female reproductive tract
Vincent et al., AIDS 2004 (HIV Infections) : Of the sera and saliva samples tested, 6/26 serum IgA and 5/25 saliva IgA inhibited the gp120-sCD4 interaction by approximately 50 % ... The gp120-sCD4 interaction was inhibited by MBP24 affinity purified IgA but not by MBP42 affinity purified IgA
Yoshino et al., J Immunol 2004 : Macaques given nasal gp120 with either mCT E112K or nCT showed elevated gp120-specific IgG and IgA Ab responses with virus neutralizing activity in both their plasma and mucosal external secretions, as well as higher numbers of gp120-specific IgA Ab-forming cells in their mucosal and peripheral lymphoid tissues and of IL-4 producing Th2-type CD4 positive ( CD4 ( + ) ) T cells than did controls