◀ Back to CCR2

CCR2 — CRP

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CCR2 → CRP (increases, CRP Translocation) Han et al., Circulation 2004*
  Evidence: Serum high-sensitivity CRP levels in 52 normocholesterolemic human subjects were positively correlated with CCR2 surface expression on circulating monocytes (r=0.62, P<0.001) and MCP-1-mediated monocyte chemotaxis (r=0.53, P<0.001). CONCLUSIONS: Elevated blood CRP levels may promote accumulation of monocytes in the atherogenic arterial wall by increasing chemotactic activities of monocytes in response to MCP-1.

Text-mined interactions from Literome

Meng et al., DNA Cell Biol 2012 : CRP stimulation may induce CCR2 overexpression on monocytes and then promote the chemotaxis ability of monocytes
Park et al., Gene 2012 : Cyclic adenosine monophosphate ( cAMP ) and the cAMP receptor protein (CRP) mediate CCR