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Quinones et al., Mol Cell Neurosci 2008
(Demyelinating Diseases...) :
Using an in vitro system we demonstrate that expression of CCR2 was functional in astrocytes and that signaling via this receptor lead to activation of NF-kB and Akt and was associated with increased astrocyte survival
Webb et al., J Leukoc Biol 2008
:
Pan-isoform inhibitors of PI-3K/Akt signaling prevented CCR2- and CCR6 mediated, polarized Th17 cell migration in a concentration dependent manner