Gene interactions and pathways from curated databases and text-mining

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BDNF — DLG4

Text-mined interactions from Literome

Hu et al., J Neurosci 2011 : BDNF induced increase of PSD-95 in dendritic spines requires dynamic microtubule invasions ... Pharmacological inhibition of MT dynamics abolished the BDNF induced increase in PSD-95
Cao et al., PLoS Biol 2013 (Angelman Syndrome) : Moreover, the association of the postsynaptic density protein PSD-95 with TrkB is critical for intact BDNF signaling, and elevated levels of Arc were found to impede PSD-95/TrkB association ... A bridged cyclic peptide ( CN2097 ), shown by nuclear magnetic resonance ( NMR ) studies to uniquely bind the PDZ1 domain of PSD-95 with high affinity, decreased the interaction of Arc with PSD-95 to restore BDNF induced TrkB/PSD-95 complex formation, signaling, and facilitate the induction of LTP in AS mice