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ABCB1 — CYP2C19

Text-mined interactions from Literome

Simon et al., N Engl J Med 2009 (Myocardial Infarction...) : We then assessed the relation of allelic variants of genes modulating clopidogrel absorption ( ABCB1 ), metabolic activation ( CYP3A5 and CYP2C19 ), and biologic activity ( P2RY12 and ITGB3 ) to the risk of death from any cause, nonfatal stroke, or myocardial infarction during 1 year of follow-up
Wu et al., Pharmacogenet Genomics 2012 (Myocardial Ischemia) : To address this issue, we assessed the relation of single nucleotide polymorphisms within genes modulating clopidogrel absorption ( ABCB1 ), metabolic activation ( CYP2B6, CYP2D6, CYP3A4, CYP2C9, and CYP2C19 ), and biologic activity ( P2RY12 ) to the response of clopidogrel as measured by ex-vivo platelet reactivity and ischemic events during half a year of follow-up