Gene interactions and pathways from curated databases and text-mining

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MIPEP — TNF

Text-mined interactions from Literome

Xavier et al., Am J Respir Cell Mol Biol 1999 : These results suggest that LPS induced MIP-2 release from alveolar epithelial cells may be mediated in part by TNF-alpha from the same cell type
Liu et al., Biochem Biophys Res Commun 2000 (Inflammation) : Moreover, it was observed that dexamethasone treatment inhibited endothelial cell expression of MIP-2 in response to TNF-alpha stimulation and markedly reduced the number of adherent neutrophils ... These data demonstrate that TNF-alpha induces expression of MIP-2 in endothelial cells and support the hypothesis that the anti-inflammatory action of dexamethasone may, at least in part, be attributable to an inhibition of MIP-2 induction on cytokine activated endothelial cells
Otto et al., J Neurochem 2002 : By contrast, induction of MIP-2 by tumour necrosis factor-alpha (TNF-alpha) involved both p42/44 MAPK and p38 MAPK
Kuwata et al., J Biol Chem 2005 : IL-1beta/TNFalpha stimulated induction of endogenous MIP-2 preceded that of sPLA2-IIA, and exogenous MIP-2 induced sPLA2-IIA dose-dependently
Wong et al., Allergy 2006 : Either SCF or TNF-alpha could induce release from HMC-1 cells of interleukin (IL)-8, monocyte chemoattractant protein (MCP)-1, regulated upon activation normal T-cell expressed and secreted ( RANTES ), and I-309, while SCF and TNF-alpha induced release of macrophage inflammatory protein (MIP)-1beta and interferon-gamma-inducible protein-10 (IP-10), respectively
Ramos et al., Eur J Immunol 2006 : We have recently shown that antigen induced neutrophil migration into the peritoneum of immunized mice is mediated by macrophage-inflammatory protein (MIP)-1alpha which interacts with CCR1 and induces the sequential release of TNF-alpha and leukotriene B ( 4 ) ( LTB ( 4 ) )
Sharma et al., Am J Physiol Lung Cell Mol Physiol 2007 (Inflammation...) : Importantly, using macrophage and epithelial coculture methods, the specific production of TNF-alpha by H/R exposed RAW264.7 cells significantly induced proinflammatory cytokine/chemokine expression ( KC, MCP-1, MIP-2 , RANTES, and IL-6 ) by MLE-12 cells
Sethu et al., PloS one 2010 (Disease Models, Animal...) : Similarly TNFalpha caused an increase in the serum levels of IL-6, MIP-1alpha and MIP-1beta : this increase in cytokine/chemokine levels was inhibited in mice where PLD1 had been silenced
Sakai et al., Cytokine 1997 : In addition, FA as well as DX reduced MIP-2 production induced by TNF-alpha