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MIPEP — TNF
Text-mined interactions from Literome
Xavier et al., Am J Respir Cell Mol Biol 1999
:
These results suggest that LPS induced
MIP-2 release from alveolar epithelial cells may be
mediated in part by
TNF-alpha from the same cell type
Liu et al., Biochem Biophys Res Commun 2000
(Inflammation) :
Moreover, it was observed that dexamethasone treatment inhibited endothelial cell expression of
MIP-2 in
response to
TNF-alpha stimulation and markedly reduced the number of adherent neutrophils ... These data demonstrate that
TNF-alpha induces expression of
MIP-2 in endothelial cells and support the hypothesis that the anti-inflammatory action of dexamethasone may, at least in part, be attributable to an inhibition of MIP-2 induction on cytokine activated endothelial cells
Otto et al., J Neurochem 2002
:
By contrast,
induction of
MIP-2 by
tumour necrosis factor-alpha (TNF-alpha) involved both p42/44 MAPK and p38 MAPK
Kuwata et al., J Biol Chem 2005
:
IL-1beta/TNFalpha stimulated induction of endogenous
MIP-2 preceded that of sPLA2-IIA, and exogenous MIP-2 induced sPLA2-IIA dose-dependently
Wong et al., Allergy 2006
:
Either SCF or
TNF-alpha could
induce release from HMC-1 cells of interleukin (IL)-8, monocyte chemoattractant protein (MCP)-1, regulated upon activation normal T-cell expressed and secreted ( RANTES ), and I-309, while SCF and TNF-alpha induced release of
macrophage inflammatory protein (MIP)-1beta and interferon-gamma-inducible protein-10 (IP-10), respectively
Ramos et al., Eur J Immunol 2006
:
We have recently shown that antigen induced neutrophil migration into the peritoneum of immunized mice is mediated by
macrophage-inflammatory protein (MIP)-1alpha which interacts with CCR1 and
induces the sequential release of
TNF-alpha and leukotriene B ( 4 ) ( LTB ( 4 ) )
Sharma et al., Am J Physiol Lung Cell Mol Physiol 2007
(Inflammation...) :
Importantly, using macrophage and epithelial coculture methods, the specific production of
TNF-alpha by H/R exposed RAW264.7 cells significantly
induced proinflammatory cytokine/chemokine expression ( KC, MCP-1,
MIP-2 , RANTES, and IL-6 ) by MLE-12 cells
Sethu et al., PloS one 2010
(Disease Models, Animal...) :
Similarly
TNFalpha caused an increase in the serum levels of IL-6,
MIP-1alpha and MIP-1beta : this increase in cytokine/chemokine levels was inhibited in mice where PLD1 had been silenced
Sakai et al., Cytokine 1997
:
In addition, FA as well as DX reduced
MIP-2 production
induced by
TNF-alpha