Gene interactions and pathways from curated databases and text-mining

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FASN — TNF

Text-mined interactions from Literome

Heimerl et al., Biochim Biophys Acta 2006 (Inflammatory Bowel Diseases) : However, in cell culture experiments using the human intestinal cell line LS174T induction of fatty acid synthase by the LXR ligand T0901317 was inhibited by TNFalpha
Dorn et al., International journal of clinical and experimental pathology 2010 (Fatty Liver...) : In vitro incubation of primary human hepatocytes with fatty acids dose-dependently induced cellular lipid-accumulation and FASN expression, while stimulation with TNF did not affect FASN levels
Liu et al., J Lipid Res 2013 : We also show that FASN overexpression suppresses tumor necrosis factor-a production and nuclear factor-?B activation as well as drug induced activation of neutral sphingomyelinase