Zhang et al., J Biol Chem 2003
:
Tumor necrosis factor (TNF) , via its receptor 2 ( TNFR2 ), induces Etk ( or Bmx ) activation and Etk dependent endothelial cell ( EC ) migration and tube formation ... However, TNF induces phosphorylation of Etk at Tyr-566, directly mediating the recruitment of the p85 subunit of PI3K
Al-Lamki et al., Am J Transplant 2009
:
In ( WT ) C57BL/6 myocardium, TNF activated both ASK1 and Etk , and increased both apoptosis and cell cycle entry