Cho et al., Immunol Lett 2007
(Arthritis, Rheumatoid) :
Thus, TLR-2 activation in RA FLS by microbial constituents could be involved in the induction of VEGF and IL-8 and thereby promote inflammation either directly or via angiogenesis
Koff et al., Am J Physiol Lung Cell Mol Physiol 2008
:
We conclude that multiple TLR ligands induce airway epithelial cell production of IL-8 and VEGF via a Duox1 -- > ROS -- > TACE -- > TGF-alpha -- > EGFR phosphorylation pathway
Grinberg et al., Am J Pathol 2009
(Inflammation) :
This switch involves induction of A ( 2A ) Rs by TLR agonists, down-regulation of tumor necrosis factor alpha (TNFalpha) and interleukin-12, and up-regulation of vascular endothelial growth factor ( VEGF ) and interleukin-10 expression
Spirig et al., PloS one 2010
:
In addition, we could show that TLR stimulation resulted in an increase of HIF-1alpha controlled VEGF secretion