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HRAS — RHOA

Pathways - manually collected, often from reviews:

• NCI Pathway Database Plasma membrane estrogen receptor signaling: RHOA/GDP complex (RHOA) → RAS family/GTP complex (HRAS_KRAS_HRAS_KRAS_NRAS) (modification, collaborate)
  Simoncini et al., Mol Endocrinol 2006
  Evidence: mutant phenotype

Text-mined interactions from Literome

de Godoy et al., Gastroenterology 2007 : H-ras inhibits RhoA/ROCK leading to a decrease in the basal tone in the internal anal sphincter
Fleming et al., Oncogene 2009 (Cell Transformation, Neoplastic) : TGF-beta mediated activation of RhoA signalling is required for efficient ( V12 ) HaRas and ( V600E ) BRAF transformation ... Furthermore, we show that ALK5 mediated activation of RhoA is required for efficient ( V12 ) HaRas , V-Raf and ( V600E ) BRAF transformation and ( V12 ) HaRas mediated anchorage independent growth