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Text-mined interactions from Literome

Sakamoto et al., J Am Coll Cardiol 2003 (Myocardial Infarction) : Effect of activated protein C on plasma plasminogen activator inhibitor activity in patients with acute myocardial infarction treated with alteplase : comparison with unfractionated heparin
Bajzár et al., J Biol Chem 1990 : The effect of human activated protein C (APC) on fibrinolysis was studied in a cell-free system by continuously monitoring the thrombin induced formation and subsequent tissue-type plasminogen activator induced degradation of fibrin
Owen et al., Arch Pathol Lab Med 1982 : ( 2 ) A second cofactor on endothelium binds thrombin in a manner that enhances by several orders of magnitude the ability of thrombin to activate protein C. ( 3 ) Activated protein C has both anticoagulant and catabolic activities ; anticoagulant activity results from the susceptibility of factors Va and VIIIa to inactivation by activated protein C, whereas catabolic activity arises from the stimulation by activated protein C of the release from endothelium of fibrin dependent plasminogen activator