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CORT — IRF6
Text-mined interactions from Literome
Mancuso et al., J Neuroimmunol 1999
:
SnPP9 given i.p. failed to modify either basal or
LPS stimulated levels of AVP and
Cort
Johnson et al., J Neuroimmunol 2006
:
Age and hormone effects on pituitary cytokines were also mirrored in plasma corticosterone (CORT) levels, such that estrogen treatment to senescent females attenuated
LPS induced
CORT
Munhoz et al., J Neurosci 2010
(Inflammation) :
In the absence of
LPS , elevated
CORT levels
increased basal activation of ERK1/2, p38, SAPK/JNK, and AKT in both regions
Cui et al., J Endocrinol 2011
:
Plasma
corticosterone (Cort) and ACTH
responses to
LPS were well maintained in pregnant rats at embryonic days 15/16 ( E15/16 ) and E18/19 compared to non-pregnant rats ... In non-pregnant animals, pretreatment with the GC synthesis inhibitor, metyrapone, inhibited the LPS induced increase in IL-6, and the IL-6 response was restored by Cort replacement, indicating that
LPS induction of IL-6 is
Cort dependent ... In E15 pregnant animals, metyrapone had no effect on LPS induced IL-6 levels, indicating that
LPS-induction of IL-6 is not
dependent on
Cort
Mekaouche et al., Neuroimmunomodulation 1994
:
In contrast, the ACTH and
CORT post-LPS responses were normal in the OR group
Givalois et al., C R Seances Soc Biol Fil 1995
:
When injected through an intra-arterial ( i. a. ) cannula,
LPS induced a rapid ( 15-30 min ) and long lasting ( > 300 min )
increase in plasma ACTH and
corticosterone (CORT) levels
Givalois et al., Neuroendocrinology 1996
:
Blockade of histaminergic receptors by intra-arterial pretreatment with H1 or H2 antagonists ( mepyramine, 1 mg/rat, and cimetidine, 2 mg/rat ), administered separately, did not affect either ACTH or
CORT responses to
LPS
Nakamura et al., Poult Sci 1998
:
This study suggests that E. coli
LPS may elevate serum IL-6 and CORT, and that IL-6 and
CORT may
increase the alpha1-AG level in the chicks