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BCL2 — IRF6
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Fortunato et al., Pancreas 2000
:
These data show that ( a ) long-term alcohol feeding suppresses apoptosis in the pancreas ; ( b )
LPS increases the rate of apoptosis in the pancreas ; ( c ) caspase-3 activity and
Bcl-2 expression change in opposite directions ; ( d ) TUNEL positivity and Fas ligand expression are increased, and Bcl-2 is decreased in ethanol fed + LPS injected rats
Cinel et al., Pharmacol Res 2002
(Endotoxemia...) :
In conclusion, 3-AB decreases LPS induced apoptosis in ileum by preventing
LPS induced depletion of
Bcl-2 and blocking iNOS gene
Liu et al., J Biol Chem 2004
:
In
response to
lipopolysaccharide (LPS) stimulation,
BCL10 was recruited to TLR4 signaling complexes and associated with Pellino2, an essential component down-stream of BCL10 in the TLR4 pathway
Sano et al., Res Vet Sci 2005
:
By real-time quantitative PCR analysis, it was indicated that
Bcl-xL and Bax levels in canine neutrophils were significantly
affected by
LPS stimulation
Yu et al., FASEB J 2005
(Inflammatory Bowel Diseases) :
Western blot showed that
LPS in high glucose
increased the levels of anti-apoptotic
Bcl-2 and Bcl-X ( L, ) and did not change proapoptotic Bax
Ramana et al., Free Radic Biol Med 2007
:
In addition, AR inhibition prevented the
LPS induced down-regulation of
Bcl-xl and up-regulation of Bax and Bak in macrophages
Lee et al., J Pineal Res 2009
(Body Weight...) :
In western blot analysis,
LPS reduced the levels of
Bcl-XL and procaspase-3 in SD mice
Cui et al., Acta Pharmacol Sin 2013
(Atherosclerosis) :
In ApoE ( -/- ) mice, administration of amiloride significantly suppressed LPS accelerated atherosclerosis and LPS induced increase of NHE1 activity, and reversed
LPS induced down-regulation of
Bcl-2 expression