Conquer et al., Osteoarthritis Cartilage 1994
:
Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes
Radeff et al., Cell Signal 2004
(Bone Resorption) :
Role of protein kinase A, phospholipase C and phospholipase D in parathyroid hormone receptor regulation of protein kinase Calpha and interleukin-6 in UMR-106 osteoblastic cells ... This is the first demonstration that PLD mediated signalling leads to both PKC-alpha translocation and IL-6 promoter activation in osteoblastic cells
Hamdi et al., Biochim Biophys Acta 2008
(MAP Kinase Signaling System) :
As a functional consequence of this PLD2 dependent MAPK activation, interleukin-2 production evoked by PMA/ionomycin stimulation or CD3/CD28 engagement was enhanced in the two T-cell lines overexpressing PLD2
L'Heureux et al., Blood 1995
:
Diverging signal transduction pathways activated by interleukin-8 and related chemokines in human neutrophils : interleukin-8 , but not NAP-2 or GRO alpha, stimulates phospholipase D activity