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IL22 — REG3G

Text-mined interactions from Literome

Kinnebrew et al., J Infect Dis 2010 (Disease Models, Animal...) : Induction of RegIIIgamma requires TLR5 expression in hematopoietic cells and is dependent on interleukin 22 expression
Kinnebrew et al., Immunity 2012 : Flagellin induced RegIII? expression is IL-22 dependent , but how TLR signaling leads to IL-22 expression is incompletely defined ... By using conditional depletion of lamina propria dendritic cell ( LPDC ) subsets, we demonstrated that CD103 ( + ) CD11b ( + ) LPDCs, but not monocyte derived CD103 ( - ) CD11b ( + ) LPDCs, expressed high amounts of IL-23 after bacterial flagellin administration and drove IL-22 dependent RegIII? production