Gene interactions and pathways from curated databases and text-mining

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GHRHR — IGF1

Text-mined interactions from Literome

Sugihara et al., Neurosci Lett 1999 : Effect of insulin-like growth factor-I on growth hormone releasing factor receptor expression in primary rat anterior pituitary cell culture ... We examined the effect of insulin-like growth factor-I (IGF-I) on GH-releasing factor (GRF) receptor expression in the primary rat anterior pituitary cell culture
Korytko et al., Growth Horm IGF Res 2001 : Taken together, these results indicate that ( 1 ) thyroid hormone and hydrocortisone act directly at the neonatal pituitary as potent stimulators of GHRH receptor gene expression, ( 2 ) IGF-I, but not IGF-II, acts at the pituitary to suppress GHRH receptor mRNA expression and ( 3 ) the effects of IGF-I on GHRH receptor gene expression are developmentally determined
Park et al., J Endocrinol 2004 (Dwarfism) : These results demonstrate that the fasting induced changes in pituitary expression of sst2 and sst5, but not GHRH-R and GHS-R, are GH/IGF-I dependent