Ma et al., Scand J Immunol 2011
(Colonic Neoplasms) :
This study aims to investigate the role of tumour derived Foxhead box P3 (Foxp3) ( + ) interleukin (IL)-17 ( + ) T cells on suppressing tumour-specific CD8 ( + ) T cells
Mattarollo et al., J Immunol 2011
:
Inhibition of CD8 T cell function did not require Foxp3 ( + ) regulatory T cells or NKT cell secreted IFN-?, IL-10, or IL-17
Gomez de Agüero et al., J Clin Invest 2012
(Dermatitis, Allergic Contact) :
Depletion and adoptive transfer experiments revealed that LCs conferred protection from development of CHS by a mechanism involving both anergy and deletion of allergen-specific CD8 ( + ) T cells and activation of a population of T cells identified as ICOS ( + ) CD4 ( + ) Foxp3 ( + ) Tregs