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CD55 — CD97

Pathways - manually collected, often from reviews:

• Reactome Reaction: CD97 → CD55 (reaction) Lin et al., J Biol Chem 2001*, Hamann et al., J Exp Med 1996*
• Reactome Reaction: CD97 → CD55 (direct_complex) Lin et al., J Biol Chem 2001*, Hamann et al., J Exp Med 1996*

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: CD55 — CD97 (in vivo) Qian et al., Immunology 1999*
• IRef Ophid Interaction: CD55 — CD97 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: CD55 — CD97 (aggregation, confirmational text mining) Qian et al., Immunology 1999*

Text-mined interactions from Literome

Liu et al., J Zhejiang Univ Sci B 2005 (Stomach Neoplasms) : Our results suggest that CD97 ( stalk ) is probably involved in the growth, invasion and aggressiveness of gastric carcinomas by binding its cellular ligand CD55
Capasso et al., J Immunol 2006 : In this study, we show that direct stimulation of CD55 on CD4 ( + ) T cells with CD97 can modulate T cell activation but does not interfere with CD55 mediated complement regulation
Karpus et al., J Immunol 2013 : In vivo, CD55 mediated downregulation of CD97 required an intact circulation and was not observed on cells that lack contact with the blood stream, such as microglia