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S100A12 — TNF

Text-mined interactions from Literome

Ballica et al., J Bone Miner Res 1999 : CGRP inhibits osteoclasts, stimulates insulin-like growth factor I and inhibits tumor necrosis factor alpha production by osteoblasts in vitro
Monneret et al., Cytokine 2000 : Since high PCT levels have been described in human sepsis, and since CGRP inhibits TNF synthesis in rats, we examined the role of these peptides in the regulation of the inflammatory response during septic shock ... In this model, PCT ( 10 ( -7 ) M ) and CGRP ( 10 ( -6 ) M ) significantly inhibit TNF production by 27 and 24 % respectively
Liu et al., Immunology 2000 : Previously we showed that calcitonin gene related peptide (CGRP) , a neuropeptide, inhibited lipopolysaccharide (LPS) induced tumour necrosis factor-alpha (TNF-alpha) production and increased interleukin (IL)-6 release at low concentrations via activation of the cAMP pathway in mouse peritoneal macrophages ( Mphi )
Fernandez et al., Cell Immunol 2001 : We recently found that CGRP induces IL-6 and TNF-alpha in long-term bone marrow cultures and that IL-6 and TNF-alpha also inhibit IL-7 responses ... In contrast, CGRP did not induce TNF-alpha in BMDMs
Cuesta et al., Neurochem Int 2002 : We found that substance P ( SP ) and calcitonin gene related peptide (CGRP) ( 0.3-1 microM ) increased , in a concentration dependent manner, the basal secretion of interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF alpha) from cultured lymphocyte enriched mononuclear cells isolated from human peripheral blood ... SP and CGRP ( 0.1 microM ) synergistically increased basal TNF alpha secretion
Yaraee et al., Int Immunopharmacol 2003 (Inflammation) : In this study, the effects of neuropeptides substance P ( SP ) and calcitonin gene related peptide (CGRP) on production of pro-inflammatory cytokines TNF and IL-1 beta by macrophages were considered
Ye et al., Am J Cardiol 2004 (Acute Disease...) : Furthermore, in vitro S100A12 secretion increased with tumor necrosis factor-alpha (TNF-alpha) stimulation, whereas intracellular levels were lower in neutrophils with the higher TNF-alpha dose, suggesting intracellular depletion
Bowen et al., J Neurochem 2006 (Alzheimer Disease) : TNF-alpha caused a coordinate increase in CGRP promoter activity
Gomes et al., Shock 2005 (Endotoxemia...) : Finally, CGRP significantly inhibits LPS induced TNF-alpha released from mouse peritoneal macrophages
Dallos et al., Neuropeptides 2006 (Inflammation) : The aims of this study were a systematic investigation of the effects of the neuropeptides substance P ( SP ), calcitonin gene related peptide (CGRP) , vasoactive intestinal polypeptide (VIP) and galanin (GAL) on the inflammatory cytokine production ( IL-1alpha, IL-8 and TNF-alpha ) of the keratinocytes, and a study of their role in the production and secretion of nerve growth factor (NGF) and its precursor molecule ( proNGF )
Durham et al., Headache 2006 (Inflammation...) : Studies in cultured trigeminal neurons demonstrate that CGRP is released from trigeminal ganglia cells, that CGRP transcription is increased under conditions mimicking neurogenic inflammation, that migraine pharmacotherapies can both reduce CGRP release and inhibit CGRP transcription, and that tumor necrosis factor-alpha (TNF-alpha) , an endogenous inflammatory mediator implicated in migraine, can stimulate CGRP transcription
Harzenetter et al., J Immunol 2007 (Endotoxemia) : In a murine model of endotoxemia, CGRP markedly attenuated serum TNF-alpha levels, and this effect was associated with the up-regulation of ICER
Wang et al., FASEB J 2009 (MAP Kinase Signaling System) : In the present study, we demonstrate that CGRP is involved in morphine tolerance by differentially regulating the ERK dependent up-regulation of IL-1beta, TNF-alpha , and microsomal prostaglandin E synthase-1 ( mPGES-1 ) in astrocytes and p38 dependent up-regulation of IL-6 in microglia in the rat spinal cord
Horii et al., Spine (Phila Pa 1976) 2011 (Intervertebral Disc Degeneration) : retrograde neurotracing and immunohistochemistry were used to investigate the effect of the tumor necrosis factor (TNF)-a inhibitor, etanercept, on calcitonin gene related peptide (CGRP) expression in dorsal root ganglion ( DRG ) neurons innervating intervertebral discs in rats
Chung et al., PloS one 2013 (Inflammation) : S100A12 did not stimulate IL-6, IL-8, IL-1ß or TNF-a production by human peripheral blood mononuclear cells but low amounts consistently reduced cytokine mRNA and protein levels induced by serum amyloid A, by ~49 % and ~46 %, respectively
Hua et al., J Neurosci 1996 : This enhancement of the peptide release by LPS was blocked by IL-1beta tripeptide antagonist Lys-D-Pro-Thr ( 10 microM ) and mimicked by IL-1beta and TNF-alpha ( 10-100 pg/ml ), suggesting that the potentiating effect of LPS on CGRP release is mediated by generation of IL-1beta and TNF-alpha
Niizeki et al., J Immunol 1997 (Dermatitis, Contact) : Fifth, CGRP induced mast cells to release TNF-alpha