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PPP2R2B — TNF

Text-mined interactions from Literome

Roach et al., Infect Immun 2005 : Our studies are the first to demonstrate an important role for the transcription factor CREB in TNF-alpha production by mycobacterium infected macrophages, as well as a role for M. avium 's induction of PP2A phosphatase activity as a mechanism to limit macrophage activation
Hong et al., J Biol Chem 2007 : Interestingly, peptides spanning CCR2 and/or LZ disrupt IKKgamma-Tax and IKKgamma-PP2A interactions and potently inhibit NF-kappaB activation by Tax and tumor necrosis factor-alpha
Meilleur et al., Endocrinology 2007 : TNF-alpha did not affect total cell Cx43-PP2A catalytic subunit interaction, but it did induce PP2A catalytic subunit recruitment to the Triton X-100 insoluble subcellular fraction, in which Cx43-gap junction plaques are recovered
Min et al., Circ Res 2008 : Endogenous AIP1-PP2A complex can be detected in the resting state, and TNF induces a complex formation of AIP1-PP2A with ASK1 ... Furthermore, TNF induced association of PP2A with ASK1 was diminished in AIP1-knockdown ECs, suggesting a critical role of AIP1 in recruiting PP2A to ASK1
Antony et al., J Biol Chem 2010 : We found that either PP2A inhibitor okadaic acid or depletion of catalytic subunit alpha of PP2A ( PP2A/Calpha ) by small interfering RNA enhanced Bcl-x ( L ) phosphorylation when activated with hydrogen peroxide and tumor necrosis factor alpha induced oxidative stress
Nizamutdinova et al., J Cell Physiol 2013 (Hyperglycemia) : Moreover, ATRA and LGD1069 reversed the decreased PP2A activity and inhibited the activation of IKK/I?Ba and gene expression of MCP-1, IL-6, and TNF-a in the hearts of Zucker diabetic fatty rats
Begum et al., Eur J Biochem 1996 : In contrast to PP-1, TNF-alpha caused a 60 % increase in PP-2A activity and insulin failed to prevent this TNF-alpha effect ... Cell-permeable ceramide analogs mimicked the TNF-alpha effect on MAPK inhibition and PP-2A activation