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OPN1LW — TNF
Text-mined interactions from Literome
Falvo et al., Proc Natl Acad Sci U S A 2000
:
Here, we show that induction of
tumor necrosis factor alpha (TNF-alpha) gene expression in T cells stimulated by engagement of the T cell receptor ( TCR ) or by virus infection
requires CBP/p300
Nakazawa et al., Int J Mol Med 2002
(Arthritis, Rheumatoid) :
Overexpression of
CBP induced p53 transcriptional activity and recovery of
TNFalpha induced inhibition
Saha et al., J Immunol 2009
:
The
induction of
CBP by
TNF-alpha was observed only in neurons, but not in astroglia and microglia, and it was contingent on the activation of transcription factor NF-kappaB ... This study illustrates a novel biological
role of
TNF-alpha in increasing neuron-specific expression of
CBP for preconditioning that may have therapeutic potential against neurodegenerative disorders
Ni et al., Carbohydr Res 2009
(Melanoma) :
Furthermore, in vivo bioassay tests indicated that
RCP-1 could remarkably enhance T and B lymphocyte proliferations, augment the phagocytosis of macrophages and
increase the
tumour necrosis factor-alpha (TNF-alpha) levels in serum
Webster et al., J Biol Chem 2013
:
TNF , acting via NF-?B, did not change the levels of CREB, Sp1, or Egr-1 binding to the Ga ( s ) promoter, but it
induced a significant reduction in the level of
CBP