Gene interactions and pathways from curated databases and text-mining

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CD59 — TNF

Text-mined interactions from Literome

Mason et al., Blood 1999 : Tumor necrosis factor alpha (TNFalpha) and interferon gamma (IFNgamma) each increased DAF expression but not CD59 or MCP expression, and a combination of these cytokines was more potent than either alone
Grubbs et al., Xenotransplantation 2003 : We found that induction of CD59 up-regulation required specific binding of the lectin to terminal alphaGal and was not induced either by soluble factors that may be released from EC by stimulation with the lectin or by TNF-alpha , IFN-gamma, or IL-1alpha
Halme et al., Mol Immunol 2009 (Hepatitis) : The expression of CD59 could be augmented by IL-1 beta, IL-6 and TNF-alpha but was suppressed by IFN-gamma
Moutabarrik et al., Lymphokine Cytokine Res 1993 : The level of CD59 was far greater than that of DAF or MCP on EC, and was slightly up-regulated by TNF-alpha and down-regulated by IL-1 beta