Cohen-Kfir et al., Endocrinology 2011
(Osteoporosis) :
Using chromatin immunoprecipitation analysis, we reveal that Sirt1 directly and negatively regulates Sost gene expression by deacetylating histone 3 at lysine 9 at the Sost promoter
Qin et al., Yi Chuan 2013
:
Transcription factors Osterix, Runx2, and Mef2c promote the SOST expression, while Sirt1 negatively regulates the SOST expression