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NOS2 — POU2F2

Text-mined interactions from Literome

Lu et al., Am J Physiol Cell Physiol 2009 : The essential role of Oct-2 in LPS induced expression of iNOS in RAW 264.7 macrophages and its regulation by trichostatin A ... Moreover, forced expression of Oct-2 by transfection of pCG-Oct-2 plasmid restored the TSA suppressed iNOS expression elevated by LPS stimulation, further indicating that Oct-2 activation is a crucial step for transcriptional activation of the iNOS gene in response to LPS stimulation in macrophages
Gay et al., Biochim Biophys Acta 1998 : We show that in contrast to the promoter of the neuronal nitric oxide synthase gene ( nNOS ) which is strongly activated by the Oct-2 octamer binding POU family transcription factor, the iNOS gene is only weakly activated by Oct-2 via its octamer motif