Nishida et al., J Biol Chem 2005
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Constitutively active Galpha(12)- or Galpha(13) induced activation of JNK and p38 MAPK , but not extracellular signal regulated kinase ( ERK ), was inhibited by diphenyleneiodonium
Kinane et al., Am J Physiol 1997
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By contrast, expression of a GTPase-deficient G alpha(i-3) in these cells reduced both their cell doubling time by 30 % and MAPK ( p42/p44 ) activity by 60 %