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CSF2 — MAP2K1

Text-mined interactions from Literome

Meja et al., Br J Pharmacol 2000 : 4. The respective MKK-1 and p38 MAP kinase inhibitors, PD 098059 and SB 203580, maximally suppressed LPS induced GM-CSF generation by > 90 %, indicating that both of these signalling cascades co-operate in the generation of this cytokine
Bandyopadhyay et al., Mol Cell Endocrinol 2008 (Prostatic Neoplasms) : Furthermore, we showed that K- and Q-stimulated GM-CSF production involves PLC, PKC, and MEK1/2 activation
Montenegro et al., Cell Prolif 2009 (Leukemia, Myeloid) : In contrast, GM-CSF induced rapid and transient phosphorylation of MEK1/2 and ERK1/2 and up-regulated cell proliferation