Hirata et al., Mol Immunol 2008
:
However, Pam3CSK4 synergistically enhanced upLPS induced DC production of IL-10 but neither IL-12 p40 nor TNF-alpha
Lombardi et al., Clin Exp Allergy 2008
(Asthma...) :
Among the three TLR2 ligands tested, the synthetic lipopeptide Pam3CSK4 is the most potent inducer of IL-12p35 and IL-10 gene expression in murine bone marrow derived DCs, as well as in purified oral myeloid DCs
Funderburg et al., Immunology 2011
:
The IL-10 induction by Pam ( 3 ) CSK ( 4 ) caused down-modulation of the co-stimulatory molecule, CD86, whereas CD86 expression was increased in monocytes exposed to hBD-3